Ion Channel Researcher

3 days ago

Melbourne, Victoria, Australia beBeeComputationalBiophysicist Full time $97,150 - $104,280
Job Opportunity

This project presents a chance for an exceptional researcher to explore the molecular mechanisms of cardiac potassium ion channels.

The goal of this research is to elucidate inactivation and drug modulation mechanisms for HERG using advanced computational approaches. This will involve employing cutting-edge methods, including molecular dynamics simulations and structural experiments.

The work is expected to have significant impact, building on recent publications in top scientific journals. It also offers excellent career prospects for a talented and driven individual.

Key Responsibilities

  1. Investigate the molecular mechanisms of the cardiac HERG potassium ion channel.
  2. Employ advanced computational methods to describe inactivation and drug modulation mechanisms for HERG.
  3. Use cutting-edge approaches, including molecular dynamics simulations and structural experiments.

Requirements

  • A PhD in physics, physical chemistry, or a related field.
  • Research experience in computation, biophysics, condensed matter physics, or physical chemistry.
  • Experience in atomistic simulations of membrane protein systems, with a preference for simulations of ion channels, particularly potassium channels.
  • Experience in statistical mechanical theory and molecular dynamics simulations for biophysical problems using existing packages.

Benefits of the Project:

This project offers the opportunity to contribute to a highly impactful area of research, with potential applications in cardiovascular medicine. The successful candidate will have access to state-of-the-art computational resources and experimental facilities, allowing for cutting-edge research and publication opportunities.

Skills and Qualifications:

The ideal candidate will have a strong background in theoretical and computational biophysics, with experience in simulating membrane protein systems. A proven track record of publishing high-quality research papers is essential. Excellent communication and teamwork skills are also required.

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