Bioinformatics Officer in Single Cell and Spatial

2 weeks ago


Greater Adelaide SA, Australia Sahmriresearch Full time

Summary

The South Australian Genomics Centre (SAGC) is a multi-institutional, national genomics and bioinformatics facility that is supported by Bioplatforms Australia (BPA) through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS). The SAGC has consolidated genomics and bioinformatics expertise in the state, with a group of ~10 genomics and bioinformatics staff working side-by-side to deliver innovative genomics and bioinformatics solutions across all areas of genomics research, including agriculture, healthcare and ecology.

As an experienced bioinformatician you will work with a relatively high degree of independence in the area of single cell and spatial omics data analysis. Single cell and spatial omics technologies available to us include the Chromium X, Visium, STomics, and NanoString technologies and we are actively collaborating with other researchers and facilities who are developing other spatial omics methods (e.g. spatial lipidomics and metabolomics).

About the role

Key responsibilities include:

- Providing end-to-end bioinformatics analysis support to our collaborators working in the single cell or spatial omics fields.
- Developing and publishing new bioinformatics pipelines, software and resources that advance capabilities in single cell and spatial omics data analysis.
- Lead the writing of reports and publications relating to your work.
- Contribute to the development and organisation of hands-on training workshops.
- Ensure successful transfer of knowledge to other members of the SAGC bioinformatics team.

About You

Essential Criteria:

- BSc, in either bioinformatics, computer science, physics, statistics or other relevant discipline
- Experience in a research, industry or bioinformatics role
- Have a deep understanding of single-cell transcriptomics data analysis
- Prior experience with, or a keen interest in, spatial transcriptomics data analysis - particularly the Visium, STomics and NanoString technologies
- Have a broad understanding of several of the following areas
- Transcriptomics: bulk RNAseq, scRNAseq, spatial transcriptomics
- Genomics: variant, haplotype and diversity analysis, genome assembly, metagenomics, epigenetics
- DevOps: version control, test driven development and continuous integration, containerisation using Docker/Singularity
- Systems biology: multi-omics data integration, statistics
- Statistics: linear models, ANOVA, hypothesis testing
- Visualisation: data visualisation and User Interface/Experience design
- Workflow systems: Snakemake and/or Nextflow
- Other omic's technology: metabolomics, proteomics
- Prior experience with at least two of the following scripting languages: bash, R, Python and Perl
- A highly collaborative person, a strong team player and an excellent communicator
- Ability to work in an organised, methodical way and to manage multiple ongoing projects
- Attention to detail and a desire to understand a project and the intricacies of the data analysis
- Prior experience working in a high-performance computing environment

Desirable Criteria:

- Prior experience working in a biomedical context
- A strong publication track record in high impact journals, patents etc
- Prior experience developing and delivering hands-on bioinformatics training

As a not-for-profit organisation, SAHMRI employees can access salary packaging options up to $15,900. Salary packaging lets you pay for things like the everyday costs of living with money from your salary before tax. This reduces your taxable income, meaning you could pay less tax and take home more of what you earn. For more information on salary packaging please see the Maxxia website.

For a copy of the position description, please click here.

Applications close: 19 November 2024
- Aboriginal and Torres Strait Islander people are strongly encouraged to apply_
- SAHMRI is a member of the Athena SWAN Science in Australia Gender Equity program. We have been awarded Bronze status for our commitment to advancing the careers of women, trans and gender diverse individuals in STEMM._

Equity & Diversity at SAHMRI

At SAHMRI, we live our commitment to equity and diversity every day: respecting people as individuals and valuing differences to create a working environment that is fair and flexible, promotes personal and professional growth and benefits from the capabilities of a diverse workforce.



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