Senior Protein Engineer

1 week ago

Sydney, New South Wales, Australia beBeeProtein Full time $143,640 - $169,000
Lead - Antibody Engineering (Biologics)

This position will be a cornerstone of our protein engineering and characterization capability, ensuring that biologics candidates are optimised for potency, specificity, stability, and developability.


Job Summary

The Principal – Antibody Engineering & Characterization will lead efforts to design, engineer and optimize therapeutic antibodies and other biologics, applying state-of-the-art protein biochemistry, molecular biophysics, and structural biology approaches.

This role involves leading antibody engineering projects from concept through to characterised candidates.


Responsibilities
  • Establish and oversee workflows for mammalian expression, purification, and biophysical analysis.
  • Apply structural biology principles to enable design and optimization, in collaboration with domain specialists.
  • Interpret and integrate biochemical, biophysical, and structural data to drive engineering decisions.
  • Guide the technical development of junior staff and contribute to the training of students.

Required Skills and Qualifications

PhD in protein engineering, structural biology, biochemistry, or related field.

Mandatory prior industry experience in therapeutic antibody or biologics development.

Demonstrated experience in antibody or protein engineering, including optimisation for stability, expression, or function.

Proficiency in protein expression (mammalian systems preferred), purification, and biophysical characterization.

Familiarity with applying structural biology concepts to protein design, with ability to collaborate effectively with structural specialists.

Strong problem-solving skills and ability to work independently within a collaborative framework.

Excellent written and verbal communication skills.

Track record of publications and/or patents in relevant areas.


Benefits

Salary: Competitive remuneration package.

Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay.

Ample opportunities for ongoing training and development.

Stimulating, diverse and highly international research environment.

Flexible work arrangements.

18 weeks paid parental leave for both parents including paid superannuation.

A range of additional leave types to meet your personal needs.

Discounted Health Insurance.

Lifestyle discounts with community partners.

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