
Senior Protein Engineering Specialist
3 days ago
Job Opportunity
This role will lead cutting-edge projects to develop therapeutic antibodies and biologics, applying state-of-the-art protein biochemistry, molecular biophysics, and structural biology techniques.
Main Responsibilities
- Oversee antibody engineering projects from conception through to candidate characterisation
- Establish and manage workflows for mammalian expression, purification, and biophysical analysis
- Apply structural biology principles to design and optimise therapeutic proteins in collaboration with domain experts
- Interpret biochemical, biophysical, and structural data to inform engineering decisions
- Guide junior staff development and contribute to student training
Required Qualifications
- PhD in a relevant field such as protein engineering, structural biology, or biochemistry
- Mandatory industry experience in therapeutic antibody or biologics development
- Demonstrated expertise in antibody or protein engineering, including stability, expression, and function optimisation
- Proficiency in protein expression (mammalian systems preferred), purification, and biophysical characterisation
- Familiarity with applying structural biology concepts to protein design and collaborating effectively with specialists
- Strong problem-solving skills and ability to work independently within a team environment
- Excellent written and verbal communication skills
- Track record of publications and/or patents in relevant areas
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