Protein Engineering Director

3 days ago

Sydney, New South Wales, Australia beBeeStructuralBiologist Full time $160,000 - $192,000
Job Overview

The role of Lead Antibody Engineer is pivotal in Garvan's Biologics Platform, responsible for designing, engineering, and developing protein-based therapeutics.

Key Responsibilities:
  • Lead antibody engineering projects from conceptualisation to candidate characterisation.
  • Establish and oversee workflows for mammalian expression, purification, and biophysical analysis.
  • Apply structural biology principles to design and optimise.
  • Interpret and integrate biochemical, biophysical, and structural data to inform engineering decisions.
  • Guide the technical development of junior staff and contribute to student training.
  • Contribute to project planning, timelines, and milestone delivery within multidisciplinary teams.
Requirements:
  • PhD in protein engineering, structural biology, biochemistry, or related field.
  • Prior industry experience in therapeutic antibody or biologics development is mandatory.
  • Demonstrated expertise in antibody or protein engineering, including optimisation for stability, expression, or function.
  • Proficiency in protein expression (mammalian systems preferred), purification, and biophysical characterisation.
  • Familiarity with applying structural biology concepts to protein design.
  • Strong problem-solving skills and ability to work independently within a collaborative framework.

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