Scientific Investigator

2 weeks ago

Brisbane, Queensland, Australia beBeeResearch Full time $82,057 - $109,246
About the Opportunity

This research project focuses on uncovering new antibiotics from microbial isolates sourced from soil and other diverse ecosystems. By integrating cutting-edge genomics, metabolomics, and biochemical screening, the team aims to identify novel compounds that target bacterial cell wall biosynthesis.

As a Postdoctoral Research Fellow, you'll collaborate with leading experts in natural products chemistry, microbial genomics, and bioinformatics. Your role will involve isolating and cultivating microbes under varied conditions, extracting and characterising novel natural products, and analysing biosynthetic gene clusters (BGCs) to uncover their potential for antibiotic production.

Key Responsibilities

  • Establish a research program, collaborate on research projects, seek and manage research funding, publish in reputable journals and participate in project discussions.

  • Undertake the cultivation, isolation, taxonomic characterisation and cryopreservation of soil microbes (i.e. bacteria and fungi).

  • Undertake large scale microbial cultivation to produce, and use semi-preparative and preparative scale chromatography (HPLC, SPE, GEL) to isolate pure bioactive microbial natural products.

  • Use spectroscopic (NMR, MS, UV-vis and polarimeter) and chemical analysis to elucidate the structures of microbial natural products.

  • Perform genomics analyses, including BGC mining, comparative genomics, and genome assembly.

  • Support and contribute to the safe and efficient operations of research group equipment, infrastructure, methodologies and protocols.

  • Accurately document all research activities in lab books and specialist databases.

This is a research-focused position, further information can be found by viewing relevant academic performance criteria.

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