Senior Research Assistant

Overview

We are growing our scientific team at ExpressionEdits and are offering an opportunity to join us in a full-time role as a Senior Research Assistant based at our laboratories in the Babraham Research Campus near Cambridge.

About ExpressionEdits:

ExpressionEdits is revolutionizing biotechnology to create therapeutics that nobody else can. We have re-invented the design of transgenes with our proprietary method of intronization, enabling sequences that incorporate both coding and non-coding DNA to express more effectively and resemble natural gene structures. Our artificial intelligence Engine guides genetic design to advance genetic production.

We are a growing startup within Cambridge’s synthetic biology community and you can join as an early member of a diverse team spanning biology, engineering, data science, and operations. Our vision is to build biology like nature.

Position overview

We are seeking a motivated Senior Research Assistant to join our team. Reporting to a senior member of our wet lab team, the role will play a key hands-on role in advancing the development and validation of the Genetic Syntax Engine by supporting various internal research initiatives. This position involves executing and reporting on planned experimental work, utilizing a diverse array of molecular biology and protein biochemistry techniques, and operating specialized laboratory equipment. The individual will work cross-functionally within the wet lab team, contributing to the development of our platform, partnership programmes and our innovative asset pipeline.

Responsibilities

- Cloning genes into a variety of vector backbones for recombinant protein expression in mammalian systems such as CHO and HEK
- Conduct nucleic acid extractions including mini, midi and maxi scales - DNA and RNA
- Transfecting cultures for transient protein production or to make stably transformed pools of cells for research applications
- Affinity purification of recombinant proteins across a diverse range of protein targets, primarily via Ni-NTA capture but could include other affinity purification methods
- Characterizing your protein products with in vitro assays (e.g. ELISA, SDS-PAGE)
- Working with others to structure experiments, collect and present data to the wider team
- Conducting your experiments with careful attention to detail and record-keeping
- Adhere to company policies and responsible health & safety practices

Qualifications, experience and skills

Qualifications and Experience:

- BSc or Master’s degree in a relevant field of biological sciences
- Previous industry experience working in a biological research laboratory
- General molecular biology skills such as PCR and cloning DNA constructs
- Experience of expressing, purifying and characterising proteins with a good understanding of how common techniques like affinity chromatography or ELISA work
- Experience with working with suspension CHO and HEK293 mammalian cell lines
- Experience of working and analysis of RNA would be an advantage (cDNA synthesis, RT-qPCR, NGS library prep etc)
- Familiarity with working environments in the biotech industry
- Past use of LIMS or e-lab notebooks for recording experimental results to high standards of detail

Skills & Attributes:

- Strong scientific integrity and attention to detail.
- Demonstrated ability to interpret data and troubleshoot protocols.
- Excellent organisational skills.
- Excellent verbal and written communication skills, with the ability to communicate effectively with other team members.
- Highly organized, proactive, adaptable with the ability to multitask effectively in a fast-paced laboratory environment.
- Strong communication and teamwork skills, fostering collaboration across teams.
- Flexible and solutions-orientated approach to work; ability to support colleagues and prioritize tasks based on shifting company priorities.
- Desire to continuous learning and professional growth; eager to develop new skills in alignment with the company’s scientific advancements.

How to apply

It is an exciting time to join ExpressionEdits. If you are interested in this position, please send your CV and a brief cover letter explaining your interest and suitability for this role to: recruitment@expressionedits.com

Please include ‘Senior Research Assistant’ in the email subject line. If you have any specific questions, you can contact us at the same email address, which will connect you with the right member of our team.

The closing date for applications is end of Friday 10th October 2025. We will assess applications on a rolling basis, so please apply promptly.

Equal opportunities

We are committed to promoting equal opportunities in employment and creating a workplace culture in which diversity and inclusion is valued and everyone is treated with dignity and respect. We have a zero-tolerance approach to discrimination. Recruitment will be conducted on the basis of merit, against objective criteria, to avoid discrimination and provide equality of opportunity. Our Equal Opportunities Policy is available upon request.

Registered address: 3rd Floor 1 Ashley Road, Altrincham, Cheshire, United Kingdom, WA14 2DT

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