Research Officer

2 weeks ago

Sydney, New South Wales, Australia The Garvan Institute Of Medical Research Full time

The Australian Genomic Cancer Medicine Centre (AGCMC, also known as Omico) is a not-for-profit, nationwide network of centres and medical research institutes that delivers precision medicine clinical trials and studies for the screening, prevention and treatment of cancers. It has a focus on patients with rare, less common and early onset cancers, and cancers with poor outcomes. The Molecular Screening and Therapeutics (MoST) program is a key component of the AGCMC, running in New South Wales since 2016 and co-ordinated at the Garvan Institute, and requires a bioinformatics research officer for operations and development.

THE OPPORTUNITY

We are seeking a Research Officer to join Prof David Thomas's research group to understand the molecular underpinnings of inherited sarcoma susceptibility. The research officer will lead and contribute bioinformatics and statistical analysis with a primary focus on statistical fine-mapping and functional bioinformatics using whole genome sequencing cohorts.

**Salary**: Up to $100,000 + 14% super dependent on experience
Employment Type: 2 year maximum term contract

SNAP SHOT OF BENEFITS
- Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom)
- Ample opportunities for on-going training and development
- Stimulating, diverse and highly international research environment
- Flexible work arrangements e.g. location, start / finish times etc
- 18 weeks paid parental leave for both parents including paid superannuation
- A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave
- Discounted Health Insurance
- Lifestyle discounts with our community partners

WHAT YOU WILL DO
- Planning and executing research
- Analysing common, rare and structural variants from whole genome sequencing datasets
- Developing methods to extract quantitative, ultra-low frequency variation from sequence data derived from tumor and blood samples.
- Develop novel computational methods to extract biological knowledge
- Develop pharmacogenomics approaches in case: control cohort

ABOUT YOU
- A PhD in bioinformatics or computational biology, or equivalent experience in a related field.
- Proficiency with genotyping of human samples using massively parallel sequencing technology.
- Expertise in integrating and merging biological databases into variant annotations
- Ability to manage and process large datasets in a POSIX environment.
- Fluency in at least one scripting language.
- Excellent communication skills and strong in team work and collaborative research
- Ability to conceptualise and execute a research plan to investigate an open-ended question, with mínimal supervision.
- A proven track record e.g. publications, grants, software/tool development
- Familiarity with the ethical issues and guidelines relating to the use of human tissue and clinical data for research
- Statistical expertise and experience with the R programming language and key libraries is highly desirable.
- Knowledge of cancer biology and evolution is highly desirable.
- Familiarity with public bioinformatics resources such as UK biobank, ENCODE etc is highly desirable.

ABOUT GARVAN

The Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia's largest and most highly regarded MRI's.

Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome.

We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease.
- Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging._

HOW TO APPLY

**Salary**: Up to $15,900.00 per month

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