Principle Investigator

2 days ago

Adelaide, South Australia On Q Recruitment Full time $120,000 - $180,000 per year

About the Role
We are seeking a number of experienced and highly motivated Principal Investigators (PI) to join our Clients Phase I-II Clinical Trial Unit. These opportunities can be permanent (4- or 5-days week) or Consultant (minimum 2 days/week with the ability to flex, complexity of study dependent). These roles are senior clinical research leadership postings with the responsibility to provide oversight and medical support for each clinical trial designated in accordance with Good Clinical Practice.

The PI will oversee protocol execution, ensure participant safety, drive high-quality data generation, and collaborate closely with sponsors, regulatory stakeholders, and cross-functional clinical teams.

Key Responsibilities

  • Provide overall medical leadership for Phase I-II clinical trials, including first-in-human studies.
  • Ensure the ethical and compliant delivery of all studies in accordance with GCP, local regulations, and organisational governance.
  • Oversee participant safety, including assessment of AEs/SAEs and real-time medical decision making.
  • Serve as the primary medical point of contact for sponsors, CROs, regulatory bodies, and internal teams.
  • Contribute to study design, protocol development, and scientific review of early-phase programs.
  • Lead and mentor clinical research staff, sub-investigators, and multidisciplinary teams.
  • Support recruitment strategies, feasibility assessments, and operational planning for new studies.
  • Represent the Unit at scientific meetings, ethics committees, and investigator forums.

Essential Qualifications & Experience

  • Medical degree (MBBS/MD). Specialist registration, preferred but not essential.
  • Current AHPRA registration.
  • Demonstrated experience as an Investigator or Sub-Investigator in early-phase clinical trials.
  • Strong understanding of GCP, early-phase methodology, and safety oversight requirements.
  • Proven ability to lead clinical teams in a high-acuity, research-driven environment.
  • Excellent clinical judgment, communication skills, and stakeholder engagement capability.

What's on Offer

  • Opportunity to lead cutting-edge early-phase research with national and international collaborators.
  • A supportive, high-performing research environment with strong clinical, scientific, and operational infrastructure.
  • Competitive remuneration package aligned with experience.

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