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Bioinformatics Specialist
2 weeks ago
Clinical Diagnostics
- NGS
- Data Analysis
**The Client**
Backed by significant Venture Capital funding, our client is a biotech start-up developing innovative technologies poised to transform the industry’s approach to quality control and longitudinal monitoring of clinical molecular diagnostics. Key to this strategy is the expansion of their widely published platform which focuses on the use of synthetic DNA and RNA ‘spike-in’ controls to increase the accuracy, performance, and quality of genomic data.
**The Opportunity**
Working as a Bioinformatics Specialist*, your key remit will be to develop and implement bioinformatic pipelines and workflows for the analysis, validation, visualisation, and interpretation of NGS data sets. These will include considerations for the design, implementation, and validation of synthetic controls representative of biomarkers that relate to the needs and requirements of customers, and the product development team.
- Design and implement bioinformatics pipelines for analysis of synthetic DNA controls and NGS data sets, including quality control, alignment, variant calling, and annotation.
- Develop and implement methods for the design of synthetic controls representing biomarkers, such as somatic mutations and copy number alterations in cancer genomes.
- Utilize existing bioinformatics tools and develop new algorithms to identify and annotate genomic variants and analyse synthetic DNA controls.
- Evaluate the performance of bioinformatics pipelines and algorithms and implement necessary improvements.
- Provide software and analytical support to strategic projects.
- Stay up-to-date with new bioinformatics tools, databases, and computational methods for NGS data analysis.
- Communicate results and findings with internal team members, as well as external clinical researchers and scientists.
**The Requirements**
- PhD in bioinformatics or related discipline, or a Masters Degree with considerable industry working with NGS data sets (ideally in the context of clinical genomics).
- Expertise in computational biology, genomics, and bioinformatics with a solid understanding of NGS protocols, statistical methods and analysis of next-generation sequencing data.
- Proficiency in analysing NGS data, such as whole-genome sequencing, cancer diagnostics, and transcriptome sequencing and in developing algorithms and bioinformatics pipelines for identifying genomic variations in cancer genomes.
- Proficiency in relevant programming languages, such as R and Python, combined with experience with variant calling and annotation tools such as GATK, SAMtools, and Annovar.
- Exceptional verbal and written communication skills accompanied by the ability to work both autonomously, and as part of a fast-paced, multidisciplinary team.
**The Offer**
mexec delivers executive recruitment solutions to the pharmaceutical, biotechnology and broader technology industries. mexec comprises of highly talented and knowledgeable industry experienced Consultants that partner with leading organisations to grow their leadership teams.
We recruit at all levels including senior management, and we are currently recruiting for a variety of opportunities in the area of Sales & Marketing, Management, Medical, Regulatory Affairs, Clinical Research, Pharmacovigilance and Operations. Contact us today.
