Molecular Genomics Researcher

15 hours ago

Sydney, New South Wales, Australia Garvan Institute of Medical Research Full time
The Opportunity

We are seeking a highly skilled and experienced molecular genomics scientist to join our team at the Garvan Institute of Medical Research. As a key member of our Translational Genomics Program, you will play a critical role in advancing our understanding of the impact of human genetic variation on diseases at the level of individual cells.

Our program focuses on developing novel therapeutic targets and companion tests to inform therapy choice. You will lead the generation of high-throughput genomics data, particularly single-cell and spatial assays, on large cohorts of clinical samples. You will also work closely with industry partners on the testing and development of early-stage technology.

Key Responsibilities:

  • Manage experiments generating single-cell data using high-throughput platforms such as 10x Genomics (single-cell and spatial), including sample preparation, cell capture, library generation, and QC.
  • Establish and maintain excellent records of molecular requirements and techniques for all projects, working closely with the bioinformatics team to ensure project meta-data is recorded for downstream analysis.
  • Identify opportunities to improve lab efficiencies and throughput in the molecular genomics workflows.
  • Work closely with key team members to provide detailed information on samples, data, and overall project progress.
  • Provide ad hoc support in other projects across the team where necessary.
  • Develop and update clear SOPs.
  • Support biobanking of primary and derived biological material necessary for the long-term development of the program.
  • Contribute to the writing and authorship of scientific publications.

Requirements:

  • BSc (Hons) or MSc in a relevant area of science and a deep understanding of genomics and molecular techniques.
  • Minimum 3 years of experience in a molecular biology lab.
  • Experience with single-cell technology or other high-throughput genomic techniques.
  • Knowledge of molecular biology protocols associated with single-cell technology and 'next-generation sequencing'.
  • Highly organised and excellent communicator.
  • The ability to assess priorities and manage competing deadlines.
  • Excellent written and oral communication, representation and interpersonal skills to interact with internal and external stakeholders.
  • An ability to work independently and efficiently within a diverse team.
  • Strong creative thinking and problem-solving skills.
  • Punctuality and being able to work flexible hours if needed.

Desirable Skills:

  • Experience in the collection and processing of human blood and tissue specimens.
  • Experience in molecular biology techniques, e.g DNA/RNA extraction.

About Garvan

The Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia's largest and most highly regarded MRI's.

Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome.

We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease.

Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture 'add', not culture 'fit' and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively.

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