Simulations Scientist For Potassium Ion Channel Research

2 days ago

Melbourne, Victoria, Australia beBeeIonChannel Full time $97,150 - $104,280

Project Overview

">

CHARMM is a versatile program for atomic-level simulation of many-particle systems, particularly macromolecules of biological interest.

">

This project presents an exciting opportunity to investigate the molecular mechanisms of the cardiac HERG potassium ion channel using advanced computational approaches.

">

The goal is to describe inactivation and drug modulation mechanisms for HERG by employing cutting-edge molecular dynamics methods.

">Key Responsibilities">
  • ">
  • Employ state-of-the-art computational techniques using supercomputers to examine HERG channel mechanisms, alongside structural and functional experiments.">
  • Collaborate with researchers at leading institutions to advance knowledge in the field.">
  • Conduct high-impact research with excellent career possibilities for a talented and driven researcher.">
">

Research Fellow Details:

">
  • ">
  • A postdoctoral position funded at RMIT Academic level A6-A8.">
  • A competitive salary range of $97,150 - $104,280 AUD per year + 17% Superannuation.">
  • An expected start date between December 2024 and February 2025.">
">

Requirements:

">
  • ">
  • A PhD in physics, physical chemistry or a closely related discipline.">
  • A research background in computation in biophysics, condensed matter physics or physical chemistry.">
  • Experience in atomistic simulations of membrane protein systems, with a strong preference for experience in simulations of ion channels, particularly potassium channels.">
  • Experience in statistical mechanical theory and molecular dynamics simulations for biophysical problems using existing packages, with strong preference for experience in NAMD/VMD and CHARMM.">
  • Background in using enhanced sampling and free energy methods, such as Umbrella Sampling and Free Energy Perturbation, with expertise in replica methods, such as Replica Exchange with Solute Tempering and Metadynamics.">
  • Strong skills in supercomputing using both CPUs and GPUs, programming/scripting in a Unix environment, MD scripting for advanced simulations and analysis, as well as good visualization skills.">
  • Able to work effectively with experimental collaborators to achieve high impact publications.">
  • Experience in paper writing, with the ability to independently form high quality paper drafts.">
  • Experience in conference presentation of research findings.">
  • High level written and verbal communication skills.">
  • Able to work autonomously whilst displaying a strong commitment to work in a team environment.">
  • Able to meet deadlines and effectively manage varying workloads and respond to changing priorities as required.">
"],

  • Senior Researcher

    2 weeks ago

    Melbourne, Victoria, Australia beBeePotassiumChannel Full time $97,150 - $104,280

    Job OpportunityInvestigate the fundamental mechanisms of potassium ion channel function and modulation in a collaborative research environment.Employ advanced molecular dynamics methods and analysis to describe potassium channel conduction, inactivation, and modulation mechanisms.Study systems including BK (Big-conductance K), MthK, and KcsA potassium...

  • Simulation Researcher

    2 weeks ago

    Melbourne, Victoria, Australia beBeePotassium Full time $97,150 - $104,280

    As a postdoctoral researcher in herg potassium ion channel simulations, you will be working on an exciting project that combines cutting-edge computational approaches with experimental collaborations.Project OverviewThis project represents a unique opportunity to investigate the molecular mechanisms of cardiac herg potassium ion channels using advanced...

  • Senior Researcher

    7 days ago

    Melbourne, Victoria, Australia beBeePotassium Full time $97,150 - $104,280

    Job OverviewThe department is seeking an accomplished researcher to investigate the molecular mechanisms of potassium ion channel function and modulation. This exciting opportunity will involve conducting cutting-edge research to expand our understanding of these complex biological systems.About the RoleWe are looking for a highly motivated individual with a...

  • Postdoctoral Researcher in BK and MthK Potassium ion channel simulations

    2 weeks ago

    Melbourne, Victoria, Australia CHARMM-GUI Full time

    CHARMM is a versatile program for atomic-level simulation ofmany-particle systems, particularly macromolecules ofbiological interest. - M. KarplusPostdoctoral Researcher in BK and MthK Potassium Ion Channel SimulationsDate2025-01-10LocationMelbourne, AustraliaDescriptionAn exciting opportunity is available for an outstanding postdoctoral researcher or PhD...

  • Computational Biophysicist

    2 weeks ago

    Melbourne, Victoria, Australia beBeePotassium Full time $97,150 - $104,280

    As a postdoctoral researcher in computational biophysics, you will investigate the molecular mechanisms of potassium ion channels using advanced simulation methods. The project focuses on BK and MthK channels, aiming to improve our understanding of their conduction, inactivation, and modulation mechanisms.This position involves employing cutting-edge...

  • Postdoctoral Researcher in Potassium Ion Channel Function and Modulation

    1 week ago

    Melbourne, Victoria, Australia beBeeResearch Full time $97,150 - $104,280

    **Job Opportunity**: An exciting postdoctoral research position is available to investigate the molecular mechanisms of potassium ion channel function and modulation.The aim of this project is to describe potassium channel conduction, inactivation, and modulation mechanisms by employing advanced molecular dynamics methods and analysis.The systems being...

  • Postdoctoral Researcher in BK and MthK Potassium ion channel simulations

    1 week ago

    Melbourne, Victoria, Australia CHARMM-GUI Full time

    CHARMM is a versatile program for atomic-level simulation ofmany-particle systems, particularly macromolecules ofbiological interest. - M. KarplusPostdoctoral Researcher in BK and MthK Potassium Ion Channel SimulationsDate2025-01-10LocationMelbourne, AustraliaDescriptionAn exciting opportunity is available for an outstanding postdoctoral researcher or PhD...

  • Postdoctoral Researcher In Herg Potassium Ion Channel Simulations

    4 weeks ago

    Melbourne, Victoria, Australia CHARMM-GUI Full time

    CHARMM is a versatile program for atomic-level simulation ofmany-particle systems, particularly macromolecules ofbiological interest.- M.Karplus Postdoctoral Researcher in h ERG Potassium Ion Channel Simulations Date2025-01-10 Location Melbourne, Australia Description This project represents an exciting opportunity for an outstanding postdoctoral researcher...

  • Computational Biophysicist in Potassium Ion Channel Simulations

    1 week ago

    Melbourne, Victoria, Australia beBeeComputationalBiophysicist Full time $97,150 - $104,280

    Postdoctoral Researcher in Potassium Ion Channel SimulationsThis is an exciting opportunity for a postdoctoral researcher to investigate the molecular mechanisms of the cardiac HERG potassium ion channel.The aim of this project is to describe inactivation and drug modulation mechanisms for HERG by employing advanced molecular dynamics methods.Research...

  • Molecular Dynamics Expert for Potassium Channel Simulations

    6 days ago

    Melbourne, Victoria, Australia beBeeSimulation Full time $97,150 - $104,280

    Research Opportunities in Potassium Ion Channel DynamicsAs a Postdoctoral Researcher, you will investigate the molecular mechanisms of potassium ion channel function and modulation using advanced molecular dynamics methods and analysis. This project involves systems including BK (Big-conductance K), MthK, and KcsA potassium channels.Key Objectives:Design and...