Research Scientist

2 days ago

Council of the City of Sydney, Australia Bondi Bio Full time

We are an ambitious cyanobacterial biologics platform company seeking an outstanding candidate for the role of Research Scientist. As a highly-motivated individual, you will specialise in design, development, delivery and testing of novel cyanobacterial biologics, including monoclonal antibodies, VLP vaccines, & therapeutic proteins. You will tackle a range of challenges as an integral part of the team, and demonstrate a high degree of flexibility, creativity, and initiative. You will have team leadership experience, be adaptable, work well collaboratively, and be able to thrive in a start-up environment.

Key Responsibilities

- Development of genetic designs in collaboration with CTO
- Creation & execution of genetic design strategies, including:
- Design of genetic biologic expression components
- Design of plasmids; Management of build & verification process
- Management of cyanobacteria strain pipeline, including sequence verification
- Working with downstream processing lead to coordinate analysis pipeline
- Support in vitro & preclinical evaluation of biologics, in collaboration with R&D team & CTO
- Updating CTO and Executive on status and timelines for biologics & preclinical material preparation
- Management of lab resources; overseeing smooth functioning of the strain engineering pipeline
- Managing preclinical material production, in collaboration preclinical testing collaborators

Education & Experience

Critical

- Ph.D. in Bioengineering, Synthetic Biology, Immunology, Microbiology, or closely-related area,
- Competent in microorganism design; hands-on experience with the latest genetic engineering tools, including multi-fragment DNA assembly, cloning, and prokaryotic transformation essential

Advantageous but not essential:

- Industrial/postdoctoral lab experience within biotechnology, immunology, vaccine development or therapeutics
- Experience engineering cyanobacteria
- VLP, mAb and therapeutic protein expression, purification, delivery or testing
- ELISA-based testing & in vitro/in vivo therapeutic characterisation
- Experience with mammalian cell culture & mAb expression
- Conducted preclinical development studies of mAbs, vaccines or therapeutic proteins
- Experience using computational tools for protein design

About the Company

Bondi Bio is an Australian biotechnology company developing a novel platform for the biomanufacture and delivery of biologics using bioengineered cyanobacteria. The platform offers a cost-effective and rapidly-scalable solution to produce monoclonal antibodies, vaccines, and therapeutic proteins. Bondi’s food-grade cyanobacteria has the potential for distributed biomanufacturing and point-of-care needle-free delivery. Bondi is working to bring next-generation biologics to market.

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