Phage Display Research Scientist

5 days ago

Council of the City of Sydney, Australia The Garvan Institute of Medical Research Full time

Location: DarlinghurstAs part of the Biologics Platform, the Phage Display Associate Scientist will support therapeutic antibody discovery and biologic engineering efforts. The role focuses on aid in designing, constructing, and optimizing and execution of phage display libraries as welwell as screening them for high-affinity antibody binders. Working in collaboration with cross-functional teams, this role will contribute to developing cutting-edge biologics from concept through preclinical stages, applying high-throughput technologies and molecular engineering techniques. **$100,000 - $110,000 + 14% super + salary packaging (depending on experience)****SNAPSHOT OF BENEFITS** Discounted Health Insurance The key responsibilities include: Phage Display Library Panning: Conduct phage display library selections against a variety of target antigens to identify high-affinity antibody binders.The key skills and experience include: Master’s Degree in Immunology, Molecular Biology, Biochemistry, Chemical Engineering, or related field, with at least 2 years of relevant experience for RA7-8 level. Strong technical proficiency in molecular biology techniques, such as restriction enzyme or scarless cloning in complex antibody formats.Demonstrated experience in phage display library construction, screening, and antibody characterization. Hands-on experience with antibody screening by ELISA and other binding assays, including the use of liquid handling automation. Familiarity with bacterial and mammalian cell culture techniques. Experience with display library design and construction. Experience with protein/antibody engineering, including affinity maturation. Familiarity with next-generation sequencing (NGS) techniques for antibody sequencing and analysis. Proficiency in bioinformatics tools and databases used in antibody discovery (e.g., Genedata Biologics).Experience with protein structural analysis software for engineering antibodies and biologics. Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome.*Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture ‘add’, not culture ‘fit’ and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively.*To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received. If you think you’re the right person for this role, we’d love to hear how your capabilities, achievements and experience set you apart.
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