Associate Scientist

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we've invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

In the plan to create a new hub for viral vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for novel vaccine platforms.

As an Associate Scientist in the Molecular Analytics team, you will be expected to contribute toward our omics-based program supporting our viral vaccines discovery efforts. You will join our diverse preclinical research and development team working on cutting-edge technologies in addition to developing new assays suitable for candidate screening and mechanism of action studies.

Key Responsibilities:

• Implement and execute next-generation sequencing (NGS) protocols for the characterization of RNA and DNA molecules of interest for vaccine research and development, and their mechanism of action.
• Execute a wide range of experiments/technical studies/tasks testing sequence identity and gene expression profiles using bulk, single cell, and/or spatial sequencing across sequencing platforms, e.g. short and long read sequencers.
• Record experimental results and present them in written/oral communications.
• Execute new methods and protocols and proactively incorporate new technology or techniques into practice with supervision.
• Collaborate with scientists throughout the organization to support NGS activities.
• Perform complex data management tasks with supervision.
• Contribute to vaccine development-related scientific investigations and publish the work in scientific journals and patent filings.

Basic Qualifications:

• Degree in Chemistry, Biology, Biochemistry, Pharmaceutical Sciences, or related scientific field.
• MS, or BS with 1+ years of experience. 
• Two or more years of experience in molecular biology, genomics, transcriptomics, and/or assay development.
• Two or more years of experience in molecular biology, including but not limited to: Nucleic acid extraction and quality control, cloning, PCR, qPCR, ddPCR, reverse transcription, RNA in vitro transcription and purification, and various NGS library preparation methods.
• Two or more years of experience in next-generation sequencing technologies (Illumina, Pacific Biosciences, Oxford Nanopore) and their applications, e.g., bulk RNA-seq, single cell omics, immune repertoire profiling.

Preferred Qualifications:

• Experience in cell biology and/or virology, including but not limited to: Cell culture, aseptic techniques, cell-based assays, viral tittering, viral genomic isolation, viral neutralization assays, ELISAs.   
• Experience in the development of fully custom or customizing commercially available NGS workflows.
• Proficiency in bioinformatics analysis of data from NGS experiments.
• Familiarity with automated high-throughput liquid-handling systems.
• Effective written and oral communication skills as well as presentation skills. Fluency in English.
• Must be detail oriented; possess problem solving skills, and the ability to handle multiple tasks.
• Able to efficiently manage uncertainty, changes in priorities and timeline restrictions.

#Vx-Cam

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together.

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $73,838 to $123,063.

The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?
Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

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GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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