Principal Investigator

About us:

Operating for more than 30 years, CMAX is Australia's longest running and most experienced clinical trial units conducting successful world-leading research for local and international clients, specialising in a range of early-phase trials and first-in-human studies.

We are proud to be a key contributor in the advancement of global medicines and technologies - from vaccines and pain control to early warning bio-devices and hormone replacement therapies, these are just a few of the many research areas for which CMAX has provided clinical trial services.

Employing more than 350 staff, CMAX is a 78-bed clinical trials unit, with a database of more than 50,000 clinical trial participants, and utilising state-of-the-art facilities, we are primely positioned, opposite the Royal Adelaide Hospital and part of the Adelaide BioMed City precinct.

About the role:

We are seeking a Principal Investigator (PI) to join our expert team. In this pivotal role, you will provide medical and scientific leadership across assigned Phase I–II clinical trials, ensuring the highest standards of patient safety, regulatory compliance and scientific integrity.

As required, all Principal Investigators also assume the responsibilities of a Sub-Investigator (SI) to cover other designated/primary Principal Investigator leave and/or unavailability.

The successful person will be responsible for:

• Lead the medical oversight of assigned studies from start-up to completion;
• Ensure compliance with GCP, ICH guidelines, and regulatory requirements;
• Provide medical input into study design and feasibility assessments;
• Conduct eligibility assessments, physical exams and medical monitoring;
• Make safety decisions, including after-hours adverse event support;
• Collaborate with sponsors, vendors, regulators and internal multidisciplinary teams;
• Contribute to staff training, quality improvement initiatives and internal education programs;
• Support fellow investigators and cover as a Sub-Investigator when required.

About you:

We are looking for a highly skilled and motivated clinician who brings:

• Current AHPRA registration with at least 5 years post-registration experience;
• Prior experience in clinical research in a similar role;
• Fellowship (preferred but not essential);
• A specialty field (advantageous but not mandatory);
• ICH GCP certification;
• ALS 1 certification (or willingness to obtain);
• Strong clinical decision-making and communication skills;
• Professional Indemnity Insurance (may be arranged depending on contract type);
• Attend and contribute to our internal 'CMAX PI School' training.

Please note - This role is suitable only for persons who reside in or relocate to South Australia as it is an onsite hands-on role. Remote or hybrid options are not available for this position. Full time is preferred, however Part time flexibility may be considered pending availability details for at least 0.8 FTE.

What We Offer:

• Opportunity to work at the forefront of innovative clinical research;
• Involvement in groundbreaking studies that shape future treatments;
• Collaborative and supportive research environment;
• Competitive remuneration and professional development opportunities.

If you are a dedicated Clinician with a passion for advancing medical science, we invite you to join our team, please apply by attaching your application letter and CV via the Apply Now function addressed to the Human Resources Manager, Kerie Chalker.

Only candidates who have the right to work unrestricted in Australia need apply for this position.

Applications will close on Friday 17 October 2025.

Please note that we may be conducting interviews during the advertisement period and retain the right to withdraw the advert should we select a successful applicant prior to the closing date.