Expert Gene Editing Process Developer

2 weeks ago

Brisbane, Queensland, Australia beBeeScientist Full time $157,000 - $178,000

Mammoth Biosciences is a biotechnology company leveraging proprietary ultracompact CRISPR systems to develop curative therapies and applications in precision diagnostics.

Job Description

We are seeking a skilled Scientist II or Senior Scientist I to join our CMC team in a hands-on, cross-functional role that blends scientific expertise with operational excellence.

This position plays a critical role in developing, optimizing, scaling, and characterizing LNP-based delivery production processes for gene editing platforms.

  • Develop and optimize LNP manufacturing processes by applying Quality by Design (QbD) principles and executing Design of Experiments (DoEs) to identify and control critical process parameters (CPPs).
  • Optimize analytical methods such as DLS, Ribogreen, HPLC-CAD, IP-RP-HPLC, and endotoxin to identify and access critical quality attributes (CQAs).
  • Interpret analytical data to assess process robustness and guide iterative development efforts.
  • Collaborate with internal teams to support process improvements and drive innovation.
  • Present scientific findings and project updates effectively in internal meetings and to external collaborators.
  • Drive technology transfer activities with external partners by preparing comprehensive technical documentation.
Required Skills and Qualifications

The ideal candidate will possess:

  • A Ph.D. in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, or a related field with minimum 3 years relevant industry experience; or M.S. with 6 years; or B.S. with 8 years.
  • Demonstrated expertise in LNP formulation and process development, including hands-on experience with microfluidic and high-shear mixing technologies.
  • Proficiency in analytical characterization techniques for LNPs, including DLS, fluorescence-based assays, and HPLC/UPLC methods.
  • Experience with in-process and drug product stability studies.
  • Proven success in applying DoEs and statistical analysis tools for process optimization.
Benefits

Our organization offers:

  • Company-paid health, vision, and dental benefits.
  • Unlimited vacation and generous sick time.
  • Company-sponsored meals and snacks.
  • Wellness, caregiver, and ergonomics benefits.
  • 401(k) with company matching.
Others

We strive to provide an inclusive and supportive work environment.

Equal opportunity employer.

  • Expert Gene Editing Process Developer

    2 weeks ago

    Brisbane, Queensland, Australia beBeeLnpdevelopment Full time $138,000 - $178,000

    Senior Scientist PositionWe are seeking a highly skilled Senior Scientist to join our CMC team in a hands-on, cross-functional role that blends scientific expertise with operational excellence. The ideal candidate will have experience in developing, optimizing, scaling, and characterizing LNP-based delivery production processes for gene editing...

  • Lnp Process Development Specialist

    2 weeks ago

    Brisbane, Queensland, Australia beBeeGeneEditing Full time $138,000 - $178,000

    Gene Editing Delivery SpecialistMammoth Biosciences is seeking a highly skilled individual to join its CMC team in a hands-on, cross-functional role that blends scientific ingenuity with operational excellence.This position is critical for developing, optimizing, scaling, and characterizing LNP-based delivery production processes for gene editing...

  • Advanced Gene Therapy Production Expert

    2 weeks ago

    Brisbane, Queensland, Australia beBeeLnpDevelopment Full time $138,000 - $178,000

    Job Title: LNP Process Development SpecialistWe are seeking a highly skilled and experienced professional to join our team as an LNP Process Development Specialist.This role is critical for developing, optimizing, scaling, and characterizing LNP-based delivery production processes for cutting-edge gene editing platforms.The ideal candidate will thrive at the...

  • Pharmaceutical Commissioning Qualification Validation Engineer Role

    7 days ago

    Brisbane, Queensland, Australia beBeePharmaceutical Full time $120,000 - $150,000

    Senior Pharmaceutical Engineer for Commissioning and ValidationWe are seeking a senior engineer to fill this key role in Australia.Key Responsibilities:Develop detailed technical documents for commissioning, qualification, and validation of pharmaceutical facilities and equipment.Lead the development of protocols and execute field verification tasks at...

  • Legislation Editing and Publishing Services Officer Grade 2

    1 week ago

    Brisbane, Queensland, Australia Queensland Government Full time

    Legislation Editing and Publishing Services Officer Grade 2Join to apply for the Legislation Editing and Publishing Services Officer Grade 2 role at Queensland Government.The Office of the Queensland Parliamentary Counsel (OQPC) is a statutory office responsible for drafting and publishing Queensland legislation. As a Legislation Editing and Publishing...

  • Legislation Editing and Publishing Services Officer Grade 2

    1 week ago

    Brisbane, Queensland, Australia Queensland Government Full time

    Legislation Editing and Publishing Services Officer Grade 2Join to apply for the Legislation Editing and Publishing Services Officer Grade 2 role at Queensland Government.The Office of the Queensland Parliamentary Counsel (OQPC) is a statutory office responsible for drafting and publishing Queensland legislation. As a Legislation Editing and Publishing...

  • Process Engineer

    2 weeks ago

    Brisbane, Queensland, Australia Prudentia Process Consulting Full time

    As a Process Engineer, you will play an important role in delivering project design and support services to the diverse portfolio of projects in our Energy / Chemicals team.We are seeking outcome-focused individuals who are highly motivated, proactive, and thrive in a challenging, multi-disciplinary environment.The salary and level of responsibility for this...

  • Formulation Process Development Expert

    1 week ago

    Brisbane, Queensland, Australia beBeeDevelopment Full time $138,000 - $178,000

    Job DescriptionThis role is designed for individuals who can combine scientific expertise with operational excellence. We are looking for someone who can effectively blend process development, analytics, and manufacturing to deliver high-quality results.Main Responsibilities:We need a professional who can design and optimize LNP manufacturing processes by...

  • Legislation Editing and Publishing Services Officer Grade 2, Premier and Cabinet

    2 weeks ago

    Brisbane, Queensland, Australia Department of Premier and Cabinet Full time $104,000 - $130,878 per year

    The Office of the Queensland Parliamentary Counsel (OQPC) is a statutory office responsible for drafting and publishing Queensland legislation.As a Legislation Editing and Publishing Officer (Grade 2) you will be part of the team responsible for editing draft legislation, preparing consolidations of Queensland's legislation, and maintaining the content of...

  • Leading Documentation Expert

    2 weeks ago

    Brisbane, Queensland, Australia beBeeDocumentation Full time $100,000 - $135,000

    Senior Content Strategist Job OverviewThe Senior Technical Writer is a senior role responsible for leading the transformation of an organization's policy and process documentation. This involves identifying gaps in existing documentation, refreshing outdated content, and creating clear, accurate, and accessible materials that support operational excellence...