Research Fellow
2 months ago
Overview:- Salary Academic Level A6-A8 ($97,150 - $104,280) + 17% Superannuation- Based at the Melbourne CBD campus
About You
- Postdoctoral researcher in HERG ion channel simulations:n_This project represents an exciting opportunity for an outstanding postdoctoral researcher (or PhD graduate) to investigate the molecular mechanisms of the cardiac HERG potassium ion channel.
The aim of this project is to describe inactivation and drug modulation mechanisms for HERG by employing advanced molecular dynamics methods. This is an NHMRC-funded project in collaboration with researchers at Victor Chang and the University of Chicago. The project will employ cutting-edge computational approaches using supercomputers, alongside structural and functional experiments, to examine HERG channel mechanisms.
The work is expected to be high impact, with related projects recently published in _Nature _and other top journals, and will provide excellent career possibilities for a talented and driven researcher.
To be successful in this position, the applicant must:
- Hold (or be about to complete) a PhD in physics, physical chemistry or a closely related discipline (see Qualifications section).- Have a research background in computation in biophysics, condensed matter physics or physical chemistry.- Have experience in atomistic simulations of membrane protein systems. A strong preference will be given to applicants with experience in simulations of ion channels, and in particular potassium channels.- Have experience in statistical mechanical theory and molecular dynamics simulations for biophysical problems using existing packages. Strong preference will be given to those with experience in NAMD/VMD and CHARMM.- Have a background in using enhanced sampling and free energy methods, such as Umbrella Sampling and Free Energy Perturbation, with expertise in replica methods, such as Replica Exchange with Solute Tempering and Metadynamics, and advanced analysis methods, such as Markov State Modelling, being desirable.- Possess strong skills in supercomputing using both CPUs and GPUs, programming/scripting in a Unix environment, MD scripting for advanced simulations and analysis, as well as good visualisation skills.- Demonstrate ability to work well with experimental collaborators to achieve high impact publications.- Demonstrate experience in paper writing. Ability to independently form high quality paper drafts is essential.- Demonstrate experience in conference presentation of research findings.- Demonstrate high level written and verbal communication skills.- Possess the ability to work autonomously whilst displaying a strong commitment to work in a team environment, including the demonstrated ability to confidently and effectively work with colleagues.- Demonstrate ability to meet deadlines and effectively manage varying workloads and respond to changing priorities as required.
About the College
The STEM College holds a leading position and expertise in the science, technology, engineering, mathematics and health (STEM) fields. We are uniquely positioned to influence and partner with industry, as never before.
STEM College is a community of exceptional STEM researchers, teachers, inventors, designers and game-changers, supported by talented professional staff. We offer higher education programs across all STEM disciplines at the Bachelor, Master and PhD levels, and ensure our students experience an education that is work-aligned and life-changing.
The College is renowned for its exemplary research in many STEM areas including advanced manufacturing and design; computing technologies; health innovation and translational medicine; nano materials and devices; and sustainable systems. Our brilliant researchers attract funding from government and industry sources.
Industry is at the heart of what we do. It ensures our research has real world impact, and our students are truly work-ready. Under the leadership of DVC STEM College & Vice President, Digital Innovation, we have established new hubs of industry-connected digital innovation and endeavour and are engaging with global STEM organisations at scale.
Our diversity and shared values empower our work, and we are proud of the College’s inclusive, caring culture. We offer a safe, dynamic work environment, and support every member of our community to achieve their potential. The College appointed Victoria’s first ever Dean of STEM, Diversity & Inclusion in 2020, and this role drives gender equity, diversity and inclusion strategies across the College.
STEM College employs 1,000 staff who deliver onshore and offshore programs to approximately 20,000 students.
We are here to positively impact the world and create the next generation of STEM leaders.
To Apply
Please submit your CV and covering letter for this position by clicking on the ‘Apply’ link at the top of this page.
Position Description - Research Fellow (Level A)
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