Research Scientist, Structural Biology
1 month ago
Who we are
Together, we’re on a mission to make good health more affordable and accessible, to help millions around the world enjoy healthier lives. It’s a mission that bonds our people across nearly 60 countries and a rich, diverse variety of nationalities and backgrounds. Working here means working with the world’s leading manufacturer of generic medicines, and the proud producer of many of the products on the World Health Organization’s Essential Medicines List. Today, at least 200 million people around the world take one of our medicines every single day. An amazing number, but we’re always looking for new ways to continue making a difference, and new people to make a difference with.
The opportunity
We are looking for a highly dynamic and motivated Research scientist to join a highly experienced scientific team with state-of-the-art facilities that performs discovery and optimisation of therapeutic antibodies.
The candidate will perform structural biology, protein purification and characterisation workflows to guide selection of antibody candidates towards lead selection.
How you’ll spend your day
You will be joining a team of skilled protein scientists, using state-of-the art tools for structural analysis and analytical assessments to rigorously characterise antibody optimisation candidates.
On a day-to-day basis, you may perform any of the following:
- Structural analysis of macromolecules
- Molecular modelling of antibodies and antibody-antigen complexes
- Multi-parametric assessments for design and optimisations of antibody sequences
- Management of CRO activities for biophysical, structural characterisations and structure determination of antigen-antibody complexes
- Implement antigen and antibody purifications, analytical characterisations (including thermostability assessment and DLS)
- Collaborative engagement with cross-functional teams to communicate project activities and timelines.
- Keep up with the emerging trends in the discipline, provide regular updates to key stakeholders through presentations, author reports, and maintain experiment records in a timely manner through the use of electronic lab notebooks.
- Train junior staff members as required.
- Provide general research/laboratory support, including ordering and maintaining consumables, interacting with suppliers
Your experience and qualifications
- PhD or equivalent experience in biochemistry, chemistry, molecular biology, biotechnology, or related discipline
- Experience in use of software for protein structure evaluation e.g. PyMOL.
- Experience in molecular modelling of proteins, protein complexes and molecular dynamics simulations would be highly regarded.
- In depth knowledge of protein purification and characterisation techniques
- Excellent understanding and practical experience on instruments such as FPLC, HPLC
- An active interest in therapeutic drug discovery and development
- Be proactive in taking on new assignments.
- Be well organised and able to coordinate multiple activities simultaneously.
Highly regarded.
• Previous experience in industry-based R&D
Enjoy a more rewarding choice
- Work with a motivated team of scientists in state-of-the-art laboratories.
- Generous leave, health, and wellbeing benefits
- Commitment to ongoing personal & professional growth via a blend of learning opportunities
- Parking available at our Macquarie Park site
- Opportunity to join a leading global organisation with a network of 37,000 employees operating in 60 markets, with 25 R&D sites
Make a difference with Teva Pharmaceuticals
- Please submit your CV and a cover letter responding to the selection criteria outlining relative keys skills and experience in relation to this role.
- Please note that only shortlisted candidates will be contacted
Reports To
Senior Research Scientist
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Teva’s Equal Employment Opportunity Commitment
Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. We are committed to a diverse and inclusive workplace for all. If you are contacted for a job opportunity, please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience.
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