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Senior Research Officer

2 months ago


Bundoora, Victoria, Australia The Walter and Eliza Hall Institute of Medical Research Full time
About the Role

We are seeking an experienced Senior Research Officer to join our team at the Walter and Eliza Hall Institute of Medical Research. As a key member of our Chemical Biology Division, you will play a critical role in driving our drug discovery efforts and advancing novel therapeutics.

Key Responsibilities
  • Lead medicinal chemistry efforts on drug discovery projects, optimizing compounds and contributing to achieving key program milestones.
  • Drive programs along discovery and development milestones using a range of platform technology and external resources.
  • Work with our medicinal chemistry team, Contract Research Organisations, and oversee the synthesis of compounds.
  • Interpret data and contribute to decision making on next steps for the project.
  • Report on progress of the medicinal chemistry team.
  • Collaborate with and mentor colleagues with diverse technical backgrounds.
Requirements
  • PhD in organic chemistry, chemical biology, medicinal chemistry, or a related discipline.
  • Experience in drug discovery and/or medicinal chemistry, including interpreting DMPK data.
  • Demonstrated ability to apply sound medicinal chemistry principles in optimisation of lead compounds.
  • High level of expertise in synthetic organic chemistry and synthetic route design.
  • Clear understanding of structural determination using NMR and MS techniques and various purification methods.
  • Outstanding academic or industrial track record, including peer-reviewed publications and/or patents.
  • Proven organisational skills and accurate record keeping.
  • Demonstration of good lab practices, with particular attention to safety.
Desirable Qualities
  • Prior experience in utilising structure-based drug design approaches, including relevant software suites.
  • Prior experience in integrating chemo-informatics into the design of lead series.
  • Ability to grasp background biology and its impact on project.
Terms of Appointment

This is a full-time position available for 18 months. Salary is Research Employee (RE) Level B ($114,170-135,568). Up to 17% superannuation and very attractive salary packaging options are available.