Research Associate
4 weeks ago
Direct message the job poster from Arovella Therapeutics ASX: ALA
Director - Research and Development at Arovella Therapeutics Ltd (ASX: ALA)Who We Are
Arovella Therapeutics (ASX: ALA) is a dynamic and growing biotechnology company pioneering the development of innovative cell therapy products in oncology. Our technology platform is based on engineered invariant natural killer T (iNKT) cells, where Arovella's lead product, ALA-101, consists of iNKT cells engineered to express a CD19-targeting chimeric antigen receptor (CAR) for the treatment of CD19 + lymphomas and leukemias. ALA-101 is being developed as an allogeneic cell therapy, which means it can be produced from healthy donor cells, manufactured at scale and delivered to multiple patients off-the-shelf. ALA-101 is advancing to clinic with a phase I clinical trial expected to commence in FY2026. Arovella's preclinical pipeline extends to solid tumour programs, where our current assets include a Claudin 18.2-targeting CAR and interleukin (IL)-12 cytokine armouring technology (IL-12-TM), with continued focus on the strategic acquisition of innovative technologies that can strengthen our cell therapy platform.
The Role
The Arovella team is seeking a motivated and suitably experienced Research Associate / Research Scientistto conduct research and development activities at our Melbourne laboratory in the Jumar Bioincubator.
Job title: Research Associate / Scientist, Research & Development
Type: Full time (on-site)
Report: Director, Research & Development
The role will also involve engagement with VP, Manufacturing & Quality and Director,Technical Operations
Key responsibilities and duties include:
- Designing and performing laboratory experiments, with a focus on engineering iNKT and T cells with CARs and accessory molecules such as IL-12-TM, performing characterisation and functional assessments.
- Data collection, documentation using an ELN, analysis and report writing.
- Contribute to data preparation for manuscripts, conference presentations (oral or poster presentations) and attendance at key scientific meetings.
To be successful in this role:
- Bachelor's / Master's / PhD degree in a relevant discipline with specific demonstrable expertise in at least one of: cellular immunology, molecular biology, cancer cell biology, immunotherapy, bioprocess engineering. The role may be tailored based on the expertise and experience of the successful candidate/s.
- Proficiency in molecular cloning techniques, lentiviral vector production and concentration, mammalian cell culture, cell co-culture assays, and flow cytometry are advantageous.
- Prior experience with primary cell engineering, CAR-T manufacturing, and advanced cell therapy product characterisation are highly desirable but not essential.
- Excellent verbal and written English technical communication skills.
- Demonstrated ability to organise and prioritise work, sometimes under time pressure.
Why Join Us?
- Be at the forefront of groundbreaking cell therapy research in oncology.
- Collaborate with a passionate, driven team dedicated to improving patient outcomes.
- Enjoy a flexible and supportive work environment with opportunities for professional growth.
In applying please provide a CV and a cover letter that addresses the key selection criteria.
Seniority level- Seniority levelEntry level
- Employment typeFull-time
- Job functionResearch, Analyst, and Information Technology
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